ZTLIDO is designed with advanced adhesion technology

The only topical lidocaine patch with proven 12-hour adhesion1,2

  • With ZTLIDO, 90% of patients experienced essentially no lift off the skin after 12 hours1
  • ZTLIDO maintained adhesion during moderate exercise, with no significant effect on pharmacokinetics1,2
  • If edges detach, they can be reattached by pressing back down1


Differences in product characteristics: ZTLIDO vs Lidoderm® Proven bioequivalence with less medication1

ZTLIDO uses less drug to provide equivalent lidocaine exposure compared to Lidoderm®.1

Peak concentrations

In clinical trials, the ZTLIDO topical system with a 1.8% concentration of 36 mg of lidocaine achieved bioequivalence to Lidoderm® 5% concentration of 700 mg. While ZTLIDO contains less medication than Lidoderm®, it delivers the same amount of lidocaine to the application site as Lidoderm® 5%.1,3

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ZTLIDO 1.8% delivers the same amount of lidocaine as Lidoderm® 5%2

ZTLIDO ComparisonLidoderm Comparison

*ZTLIDO 1.8%: 43.99 ± 17.62 mg/3 topical systems; Lidoderm®  5%: 43.74 ± 18.22 mg/3 patches

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Differences in product characteristics: ZTLIDO vs Lidoderm®2
LighterEasy to useGreater than ten times more bioavailable
How to apply ZTLIDO

Your patients can learn how to properly apply and remove ZTLIDO by viewing the video at ZTLIDO.com.

See video on patient site

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Request samples to get your patients started

Request Samples

Patient support

Let your patients know about savings and support available to them for ZTLIDO.


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